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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 1
1980 1
1982 2
1983 1
1984 3
1985 3
1986 2
1987 1
1988 3
1989 1
1990 2
1991 3
1992 3
1993 3
1994 8
1995 2
1996 1
1998 4
1999 6
2000 7
2001 10
2002 9
2003 9
2004 14
2005 19
2006 27
2007 18
2008 22
2009 13
2010 24
2011 36
2012 31
2013 25
2014 27
2015 31
2016 40
2017 40
2018 36
2019 43
2020 58
2021 67
2022 98
2023 139
2024 66

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882 results

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Page 1
Decoding molecular and cellular heterogeneity of mouse nucleus accumbens.
Chen R, Blosser TR, Djekidel MN, Hao J, Bhattacherjee A, Chen W, Tuesta LM, Zhuang X, Zhang Y. Chen R, et al. Nat Neurosci. 2021 Dec;24(12):1757-1771. doi: 10.1038/s41593-021-00938-x. Epub 2021 Oct 18. Nat Neurosci. 2021. PMID: 34663959 Free PMC article.
In this study, we generated a cell census of the mouse NAc using single-cell RNA sequencing and multiplexed error-robust fluorescence in situ hybridization, revealing a high level of cell heterogeneity in this brain region. ...
In this study, we generated a cell census of the mouse NAc using single-cell RNA sequencing and multiplexed error-robust fluorescence in sit …
Decoding the molecular heterogeneity of pediatric monomorphic post-solid organ transplant lymphoproliferative disorders.
Salmerón-Villalobos J, Castrejón-de-Anta N, Guerra-García P, Ramis-Zaldivar JE, López-Guerra M, Mato S, Colomer D, Diaz-Crespo F, Menarguez J, Garrido-Pontnou M, Andrés M, García-Fernández E, Llavador M, Frigola G, García N, González-Farré B, Martín-Guerrero I, Garrido-Colino C, Astigarraga I, Fernández A, Verdú-Amorós J, González-Muñíz S, González B, Celis V, Campo E, Balagué O, Salaverria I. Salmerón-Villalobos J, et al. Blood. 2023 Aug 3;142(5):434-445. doi: 10.1182/blood.2022019543. Blood. 2023. PMID: 37053555 Free article.
The molecular profile of pediatric monomorphic PTLDs (mPTLDs) has not been elucidated, and it is unknown whether they display similar genetic features as their counterpart in adult and immunocompetent (IMC) pediatric patients. ...We performed an integrated molecular approa …
The molecular profile of pediatric monomorphic PTLDs (mPTLDs) has not been elucidated, and it is unknown whether they display similar gen …
Wnt Signaling Shapes the Histologic Variation in Diffuse Gastric Cancer.
Togasaki K, Sugimoto S, Ohta Y, Nanki K, Matano M, Takahashi S, Fujii M, Kanai T, Sato T. Togasaki K, et al. Gastroenterology. 2021 Feb;160(3):823-830. doi: 10.1053/j.gastro.2020.10.047. Epub 2020 Nov 17. Gastroenterology. 2021. PMID: 33217450 Free article.
METHODS: Seven patient-derived diffuse GC organoid lines were established, characterized by histopathologic analysis, in situ hybridization, and gene expression analysis. For genetic modeling of diffuse GC, we knocked out CDH1 and/or TP53 in human normal gastric org …
METHODS: Seven patient-derived diffuse GC organoid lines were established, characterized by histopathologic analysis, in situ hybridizati …
Engineered tRNAs suppress nonsense mutations in cells and in vivo.
Albers S, Allen EC, Bharti N, Davyt M, Joshi D, Perez-Garcia CG, Santos L, Mukthavaram R, Delgado-Toscano MA, Molina B, Kuakini K, Alayyoubi M, Park KJ, Acharya G, Gonzalez JA, Sagi A, Birket SE, Tearney GJ, Rowe SM, Manfredi C, Hong JS, Tachikawa K, Karmali P, Matsuda D, Sorscher EJ, Chivukula P, Ignatova Z. Albers S, et al. Nature. 2023 Jun;618(7966):842-848. doi: 10.1038/s41586-023-06133-1. Epub 2023 May 31. Nature. 2023. PMID: 37258671 Free PMC article.
Nonsense mutations are the underlying cause of approximately 11% of all inherited genetic diseases(1). Nonsense mutations convert a sense codon that is decoded by tRNA into a premature termination codon (PTC), resulting in an abrupt termination of translation. ...He …
Nonsense mutations are the underlying cause of approximately 11% of all inherited genetic diseases(1). Nonsense mutations convert a s …
Urochordate genomes.
Satoh N, Kawashima T, Shoguchi E, Satou Y. Satoh N, et al. Genome Dyn. 2006;2:198-212. doi: 10.1159/000095105. Genome Dyn. 2006. PMID: 18753780 Review.
Urochordates consist of larvaceans, ascidians, and thaliaceans. The draft genome has been decoded in ascidians, Ciona intestinalis and C. savignyi. The C. intestinalis genome is composed of approximately 160 Mbp, similar to other invertebrate genomes, and contains approxim …
Urochordates consist of larvaceans, ascidians, and thaliaceans. The draft genome has been decoded in ascidians, Ciona intestinalis an …
Bacterial wobble modifications of NNA-decoding tRNAs.
Nilsson EM, Alexander RW. Nilsson EM, et al. IUBMB Life. 2019 Aug;71(8):1158-1166. doi: 10.1002/iub.2120. Epub 2019 Jul 8. IUBMB Life. 2019. PMID: 31283100 Free PMC article. Review.
The structural basis for many N34 modifications in both tRNA aminoacylation and ribosome decoding has been elucidated, and evolutionary conservation of modifying enzymes is also becoming clearer. ...
The structural basis for many N34 modifications in both tRNA aminoacylation and ribosome decoding has been elucidated, and evolutiona …
Genomics and cancer.
Onyango P. Onyango P. Curr Opin Oncol. 2002 Jan;14(1):79-85. doi: 10.1097/00001622-200201000-00014. Curr Opin Oncol. 2002. PMID: 11790985 Review.
Genetic and environmental factors are responsible for the genomic lesions that cause cancer, a complex genetic disease associated with genomic instability. Studies aimed at deciphering the lesions in cancer have focused mainly on one or a few genes, despite the geno …
Genetic and environmental factors are responsible for the genomic lesions that cause cancer, a complex genetic disease associa …
HSNet: A hybrid semantic network for polyp segmentation.
Zhang W, Fu C, Zheng Y, Zhang F, Zhao Y, Sham CW. Zhang W, et al. Comput Biol Med. 2022 Nov;150:106173. doi: 10.1016/j.compbiomed.2022.106173. Epub 2022 Oct 5. Comput Biol Med. 2022. PMID: 36257278
For alleviating the bottlenecks, we investigate a hybrid semantic network (HSNet) that adopts both advantages of Transformer and convolutional neural networks (CNN), aiming at improving polyp segmentation. Our HSNet contains a cross-semantic attention module (CSA), a hy …
For alleviating the bottlenecks, we investigate a hybrid semantic network (HSNet) that adopts both advantages of Transformer and conv …
Synonymous Codons: Choose Wisely for Expression.
Brule CE, Grayhack EJ. Brule CE, et al. Trends Genet. 2017 Apr;33(4):283-297. doi: 10.1016/j.tig.2017.02.001. Epub 2017 Mar 12. Trends Genet. 2017. PMID: 28292534 Free PMC article. Review.
The genetic code, which defines the amino acid sequence of a protein, also contains information that influences the rate and efficiency of translation. ...The prevailing model was that the slow translation of codons decoded by rare tRNAs reduces efficiency. R …
The genetic code, which defines the amino acid sequence of a protein, also contains information that influences the rate and e …
Bispectrum-based hybrid neural network for motor imagery classification.
Liu C, Jin J, Daly I, Sun H, Huang Y, Wang X, Cichocki A. Liu C, et al. J Neurosci Methods. 2022 Jun 1;375:109593. doi: 10.1016/j.jneumeth.2022.109593. Epub 2022 Apr 6. J Neurosci Methods. 2022. PMID: 35398087
NEW METHOD: In this study, we proposed a novel framework, termed a bispectrum-based hybrid neural network (BHNN), to make full use of bispectrum for improving the performance of the MI-based brain-computer interface (BCI). ...CONCLUSION: The proposed BHNN is a novel bispec …
NEW METHOD: In this study, we proposed a novel framework, termed a bispectrum-based hybrid neural network (BHNN), to make full use of …
882 results